For a generation now, science has known of two cannabinoid receptors—specialized protein molecules that interact with the active compounds in the cannabis plant for the human body. These are CB1 and CB2, both discovered in the early '90s. Now there is growing awareness of a third such receptor that was identified in 2007. This receptor, GPR55, may be key to understanding a wide spectrum of therapeutic applications for cannabinoids—and especially the non-psychoactive cannabidiol, or CBD.

Canada is about to make history, with passage of its cannabis legalization bill imminent. Prime Minister Justin Trudeau is the man of the hour, shepherding the first Western industrialized country along a course that was nearly unthinkable a generation ago. But it was activist efforts that really brought Canada to this point—and advocates are still fighting to keep a place for small growers and vendors in the new system.
The government of New Zealand has announced that it plans to hold a referendum on cannabis legalization, possibly as early as next year. A medical marijuana bill is already pending in the country's parliament. But it has taken generations of activist effort by Kiwis to bring Aotearoa (by the country's indigenous Maori name) to this point. Cannabis Now speaks with some of the leaders who made it happen.
A big multi-agency "reclamation" effort on national forest lands in the Emerald Triangle points again to the serious environmental impacts of outlaw cannabis cultivation. Will this be the last gasp of this sort of thing now that California has legalized?
A deadly five-car pile-up on a Bay Area freeway brings into sharp focus the questions around cannabis use and road safety. Media exploitation of such carnage as propaganda against legalization, however, is missing some critical points.
New York City's Cannabis Parade, flagship entry in the Global Marijuana March movement and a counterculture event dating back to the early 1970s, this year actually drew mainstream politicians and candidates. Nearly all struck themes of racial justice, emphasizing that a push for legalization in the Empire State must also address the social iniquities of cannabis prohibition and the "war on drugs."
Going on two years after the US territory of Guam approved a medical marijuana measure by voter initiative, the program remains stalled over the supposed lack of any laboratory on the island to carry out quality control. Patients and their advocates charge that the island's government is bottle-necking the program by failing to sufficiently fund it. At heated public hearings on the issue last week in the island's legislature, advocates accused authorities of violating the will of the voters.
With Moscow accused of all manner of sinister shenanigans on the global stage, calls are mounting for a boycott of the World Cup, which is scheduled to be held in Russia this summer. Among the cases drawing special ire from rights groups is that of the leading human rights activist in Chechnya—now imprisoned on a "blatantly fabricated" cannabis charge.





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