The Oklahoma Board of Health has issued new rules to oversee the state's medical marijuana program, and advocates are relieved that the ban on smokable herbaceous cannabis has been removed. However, concerns remain about other restrictions that could make it essentially impossible for cannabis business to function in the state.

Israel's Knesset overwhelmingly passed a cannabis decriminalization measure—sponsored by the ruling conservative government. This fruit of a long campaign by activists is, however, tentative. The law is set to expire in three years, pending a review of the policy's impacts.
Compassionate care—providing medical marijuana to the ill—was what first opened legal space for cannabis in California a generation ago. But the state's Adult Use of Marijuana Act only regulates commercial businesses—leaving caregivers in legal limbo.
The election of Andres Manuel Lopez Obrador—known by his initials AMLO—as Mexico's next president is being hailed as historic, marking the first time a candidate of the left has had his victory honored. He is pledging a new, demilitarized approach to ending the endemic narco-violence. And his newly named interior minister is a vocal supporter of cannabis legalization. Will a day-lightened cannabis sector provide a way out of Mexico's long crisis?
In another sign of turning tides, a prestigious British think-tank once beloved of Margaret Thatcher has called on the government to legalize cannabis. The breakthrough report finds that a legal cannabis industry could raise £1 billion per year in tax revenues for the United Kingdom, while undercutting the black market.
The doctrine of nullification has a long and harshly contested legacy in the history of the United States—it has been invoked in defense of both just causes and frankly evil ones. But some argue that it is time to revisit the idea—to put an end to federal cannabis prohibition.
For a generation now, science has known of two cannabinoid receptors—specialized protein molecules that interact with the active compounds in the cannabis plant for the human body. These are CB1 and CB2, both discovered in the early '90s. Now there is growing awareness of a third such receptor that was identified in 2007. This receptor, GPR55, may be key to understanding a wide spectrum of therapeutic applications for cannabinoids—and especially the non-psychoactive cannabidiol, or CBD.





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