Global Ganja Report

The doctrine of nullification has a long and harshly contested legacy in the history of the United States—it has been invoked in defense of both just causes and frankly evil ones. But some argue that it is time to revisit the idea—to put an end to federal cannabis prohibition.

For a generation now, science has known of two cannabinoid receptors—specialized protein molecules that interact with the active compounds in the cannabis plant for the human body. These are CB1 and CB2, both discovered in the early '90s. Now there is growing awareness of a third such receptor that was identified in 2007. This receptor, GPR55, may be key to understanding a wide spectrum of therapeutic applications for cannabinoids—and especially the non-psychoactive cannabidiol, or CBD.

In the latest testament to fast-growing mainstream embrace of cannabis, Netflix this month debuts a competitive cooking show exclusively featuring dishes prepared with the herb. And not just for flavoring—under the show's rules, all recipes must actually get you high.

With US stock exchanges still almost entirely closed to cannabis businesses, the stateside industry is increasingly seeking access to the Canadian exchanges in order to secure investment. Taking over publicly traded Canadian firms through reverse mergers has emerged as the critical tactic in this endeavor.

In Humboldt County, famed as the heartland of Northern California's cannabis-producing Emerald Triangle, big police raids of cultivation sites—with thousands of plants eradicated—are continuing despite the Golden State's new legalization program. Many growers are choosing to remain underground, in spite of the risks to their property and freedom. And a big part of the reason why seems to lie in a confusing and contested county regulation regime.

A big multi-agency "reclamation" effort on national forest lands in the Emerald Triangle points again to the serious environmental impacts of outlaw cannabis cultivation. Will this be the last gasp of this sort of thing now that California has legalized?

A deadly five-car pile-up on a Bay Area freeway brings into sharp focus the questions around cannabis use and road safety. Media exploitation of such carnage as propaganda against legalization, however, is missing some critical points.

California's Gov. Jerry Brown has unveiled a special investigative force to go after unregistered cannabis growers. This is certainly bad news for the many growers who have failed to register because they consider the taxes and regulations burdensome. In the face of disappointing tax revenues from legal cannabis, is the state using the stick of enforcement rather than the carrot of lower taxes and more favorable regulations to bring more growers in from the shadows?